evaluation of fluoxtinfor treatm ent of menopausal hot flashes

introduction: hot flashes can be prominent problem in menopausal women. the treatment of hot flashes is hormonal thrapies but in some patients that are unable to use estrogen other treating hot flashes are required. based on anecdotal information reqarding the efficacy of fluoxtin for treating hot flashes , the present trial was developed . methods: this trial used a double blinded randomized to study the effecacy of fluoxetin (20mg/day) and comparing with placebo in treating hot flash in 4 week treatment. results: 310 women began protocol thrapy. in two group: a (flouxetine) and b-( placebo ) by the end of protocol hot flashes frequeney decreased 77.5 % with floxetin versus 13.7 % whith placebo( p=.0001)the flouxetin was well tolerated . conclusion: flouxetin resulted well improvent in hot flashes.